Coefficient of Inbreeding Formula:
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The Coefficient of Inbreeding (COI) is a measurement of the probability that two alleles at any locus in an individual are identical by descent from a common ancestor. In dog breeding, it helps quantify the genetic relatedness between parents.
The calculator uses the COI formula:
Where:
Explanation: The equation calculates the probability that two alleles are identical by descent, with the exponent representing the number of meioses between the common ancestor and the individual.
Details: COI is crucial in dog breeding to manage genetic diversity, reduce the risk of inherited disorders, and maintain overall breed health. Lower COI values generally indicate better genetic diversity.
Tips: Enter the number of common ancestors and the generational distance from both sire and dam. All values must be non-negative integers.
Q1: What is considered a high COI in dog breeding?
A: Generally, a COI below 5% is considered low, 5-10% moderate, and above 10% high. Breed-specific recommendations may vary.
Q2: How does COI affect dog health?
A: Higher COI increases the risk of inherited disorders and reduces genetic diversity, which can impact overall health and vitality.
Q3: Can COI be reduced in a breeding program?
A: Yes, by carefully selecting unrelated mates and introducing new bloodlines, breeders can gradually reduce COI over generations.
Q4: How far back should pedigrees be analyzed for COI calculation?
A: Most experts recommend analyzing at least 5-10 generations for an accurate COI calculation.
Q5: Are there breed-specific COI considerations?
A: Yes, some breeds with smaller gene pools may have naturally higher COIs, requiring careful management to maintain genetic health.